FGF19 and FGF21 serum concentrations in human obesity and type 2 diabetes behave differently after diet-or surgically-induced weight loss
J Gómez-Ambrosi, JM Gallego-Escuredo, V Catalán… - Clinical Nutrition, 2017 - Elsevier
Background & aims Fibroblast growth factor 19 (FGF19) and 21 (FGF21) have emerged as
key regulators of energy homeostasis. Our aim was to analyze the impact of weight loss
(WL) induced either by conventional dietary treatment (CDT) or bariatric surgery on FGF19
and FGF21 concentrations. Furthermore, the diverse effect of sleeve gastrectomy (SG)
versus RYGB (Roux-en-Y gastric bypass) as two surgical procedures that affect the
gastrointestinal anatomy and physiology differently was also analyzed. Methods Serum …
key regulators of energy homeostasis. Our aim was to analyze the impact of weight loss
(WL) induced either by conventional dietary treatment (CDT) or bariatric surgery on FGF19
and FGF21 concentrations. Furthermore, the diverse effect of sleeve gastrectomy (SG)
versus RYGB (Roux-en-Y gastric bypass) as two surgical procedures that affect the
gastrointestinal anatomy and physiology differently was also analyzed. Methods Serum …
